Apo-Gliclazide MR Drug Interactions

Serious Drug Interactions: APO-GLICLAZIDE MR (gliclazide) should not be taken if miconazole (an anti-fungal drug) is also being taken (see Contraindications).
Other drugs that may interact with APO-GLICLAZIDE MR: other antidiabetic agents; antibiotics (sulfonamides/sulfa drugs, clarithromycin); anti-tuberculosis drugs; anti-fungal drugs (fluconazole); non-steroidal anti-inflammatory drugs (NSAIDs) including phenylbutazone (used to treat inflammation and pain); corticosteroids (used to treat inflammation); salicylates (e.g. acetylsalicylic acid); angiotensin-converting enzyme (ACE) inhibitors (used to treat high blood pressure and certain heart conditions); beta blockers (used to treat high blood pressure and certain heart conditions); anticoagulant therapy (blood thinners), including warfarin; diuretics (thiazides, furosemide) (used to treat high blood pressure and certain heart conditions); fibrates, nicotinic acid (used to treat high levels of fats in the blood); H2-receptor antagonists (used to treat acid reflux/heartburn); monoamine oxidase inhibitors (used to treat depression); chlorpromazine (used to treat certain psychiatric conditions); probenecid (used to treat high levels of uric acid in the blood and gout); salbutamol, terbutaline (used to treat asthma) and ritodrine; barbiturates (sedatives, anti-seizure medications); oral contraceptives (estrogen plus progestogen, used for birth control); danazol (used to treat breast cysts and endometriosis); alcohol.
Some of the drugs previously described may lead to loss of blood sugar control (high blood sugar), including diuretics, corticosteroids, oral contraceptives, chlorpromazine, ritodrine, salbutamol, terbutaline, danazol and nicotinic acid.
Avoid drinking alcoholic beverages and taking medicines containing alcohol while taking APO-GLICLAZIDE MR as this can lead to a drop in blood sugar (hypoglycemia).
Tell the doctor if any of the medicines previously listed or any other medicines, including those obtained without a prescription, have recently been taken. Do not take other medicines unless prescribed or approved by the doctor. Tell any healthcare professionals that APO-GLICLAZIDE MR is being taken.