Avorix Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Entecavir

Indications/Uses

Chronic HBV infection in adults w/ evidence of active viral replication & either evidence of persistent elevations in serum aminotransferases (ALT/AST) or histologically active disease.

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Dosage/Direction for Use

Compensated liver disease Nucleoside-naive patient 0.5 mg once daily. Lamivudine-refractory patient 1 mg once daily. Decompensated liver disease 1 mg once daily.

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Overdosage

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Administration

Should be taken on an empty stomach: In nucleoside naive patients w/ compensated liver disease, take w/ or w/o meals. For patients w/ decompensated liver disease & lamivudine-refractory patients w/ compensated liver disease, take on an empty stomach (at least 2 hr before & at least 2 hr after a meal).

Contraindications

Hypersensitivity.

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Special Precautions

Not recommended for HIV/HBV co-infected patients not receiving highly active antiretroviral therapy. Not proven to reduce HBV transmission. Lactic acidosis/hepatomegaly w/ steatosis. Monitor hepatic function at repeated intervals after discontinuation. Evaluate renal function prior to & during therapy in liver transplant recipients receiving cyclosporine or tacrolimus. Closely monitor clinical & lab parameters in patients w/ decompensated liver disease. May affect ability to drive & use machines. Renal impairment. Pregnancy. Not to be used during lactation. Ped patients <16 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache; fatigue; diarrhea, dysgeusia.

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Drug Interactions

Increased serum conc w/ products reducing renal function or competing for active tubular secretion. Decreased absorption w/ food.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Avorix detailed prescribing information

Storage

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Description

View Avorix description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antivirals

ATC Classification

J05AF10 - entecavir ; Belongs to the class of nucleoside and nucleotide reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.

Regulatory Classification

Presentation/Packing

Form

Avorix FC tab 0.5 mg

Packing/Price

1 × 10's;10 × 10's;100 × 10's;3 × 10's;50 × 10's;6 × 10's

Avorix

entecavir

Manufacturer:

Novugen Pharma

Distributor:

Novugen Pharma